Proposed new clinicopathological surrogate definitions of luminal A and luminal B (HER2-negative) intrinsic breast cancer subtypes
نویسندگان
چکیده
منابع مشابه
Mammographic findings in different breast cancer subtypes (luminal, Her2 positive, triple negative)
Background: Prognosis and management of breast cancer are defined by different variables including histological type, grading, clinical stage, Her2+, estrogen and progesterone receptor conditions. Generally, mammography is one of the most important imaging which is done in breast cancer patients. The aim of this research was to evaluate different mammographic patterns in different breast cancer...
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BACKGROUND Recently, we reported cytoskeleton-associated protein2 (CKAP2) as a possible new prognostic breast cancer marker. However, it has not yet been applied in clinic. Therefore, clinical significance of CKAP2 was evaluated in comparison with that of Ki-67 in a cohort of breast cancer patients, and the expression difference was analyzed in cell cycle-arrested cancer and fibroblast cells. ...
متن کاملMRI texture analysis in differentiating luminal A and luminal B breast cancer molecular subtypes - a feasibility study
BACKGROUND The aim of this study was to use texture analysis (TA) of breast magnetic resonance (MR) images to assist in differentiating estrogen receptor (ER) positive breast cancer molecular subtypes. METHODS Twenty-seven patients with histopathologically proven invasive ductal breast cancer were selected in preliminary study. Tumors were classified into molecular subtypes: luminal A (ER-pos...
متن کاملDefinition of p53 overexpression and its association with the clinicopathological features in luminal/HER2-negative breast cancer.
AIMS A suitable cut-off value for p53 overexpression and its usefulness as a prognostic factor in luminal/HER2-negative breast cancer were evaluated. PATIENTS AND METHODS A retrospective analysis of 1,987 patients with luminal/HER2-negative breast cancer who underwent surgery between 2001 and 2009 was performed. RESULTS p53 expression ≥50% was present in 9% of the patients. Moreover, these ...
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ژورنال
عنوان ژورنال: Breast Cancer Research
سال: 2014
ISSN: 1465-542X
DOI: 10.1186/bcr3679